Biphasic Blood Flow in Mesentery Microcirculatory Networks

نویسنده

  • Jesse Gerringer
چکیده

The purpose of this paper is to investigate how changes in the plasma skimming coefficient affect the hemoconcentration within blood vessel networks. Due to the differences in plasma and red blood cells (RBCs) phases, the RBCs tend to flow at a different rate causing a difference in hematocrit concentration at a bifurcation in a network. This can be quite important when looking into how efficiently tissues are being oxygenated, especially in important regions such as mesentery tissue. This paper will analyze a plasma skimming coefficient model and attempt to utilize a polynomial fit to form a new model to see if improvements can be made by decreasing the number of variables.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Hematocrit distribution and tissue oxygenation in large microcirculatory networks.

OBJECTIVE Oxygen tension in the brain is controlled by the microcirculatory supply of RBC, but the effect of non-Newtonian blood flow rheology on tissue oxygenation is not well characterized. This study assesses different biphasic blood flow models for predicting tissue oxygen tension as a function of microcirculatory hemodynamics. METHODS Two existing plasma-skimming laws are compared agains...

متن کامل

Blood flow in microvascular networks. Experiments and simulation.

A theoretical model has been developed to simulate blood flow through large microcirculatory networks. The model takes into account the dependence of apparent viscosity of blood on vessel diameter and hematocrit (the Fahraeus-Lindqvist effect), the reduction of intravascular hematocrit relative to the inflow hematocrit of a vessel (the Fahraeus effect), and the disproportionate distribution of ...

متن کامل

Microcirculatory Networks by Hemodilution

The effect of isovolemic hemodilution on red blood cell flow distribution was studied in complete self-contained microvessel networks of the rat mesentery. Hematocrit, diameter, and length of all vessel segments as well as the topological structure were determined in control networks (systemic hematocrit, 0.54) and after hemodilution (systemic hematocrit, 0.30). Hemodilution was performed by ex...

متن کامل

Redistribution of red blood cell flow in microcirculatory networks by hemodilution.

The effect of isovolemic hemodilution on red blood cell flow distribution was studied in complete self-contained microvessel networks of the rat mesentery. Hematocrit, diameter, and length of all vessel segments as well as the topological structure were determined in control networks (systemic hematocrit, 0.54) and after hemodilution (systemic hematocrit, 0.30). Hemodilution was performed by ex...

متن کامل

Quantitative studies of microcirculatory structure and function. III. Microvascular hemodynamics of cat mesentery and rabbit omentum.

We made simultaneous measurements of intravascular pressure and red blood cell velocity for vessels which make up the modular configuration of microvascular networks in mesentery and omentum. An analysis of these variables and the computed volumetric flow rates is presented for arterioles which had a maximum diameter of 56 micrometer through the "true capillaries" (typically 7 micrometer for me...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015